Honinbo Sansa (本因坊算砂 Hon'inbō Sansa, 1559-1623) was a famous Go player.

Sansa was the first head of the Honinbo house and the first Meijin, taking the name Sansa. Sansa was the rival of Kashio Rigen. He was also a strong shogi player. He was a Buddhist priest of the Nichiren sect and his original name was Nikkai. He lived in a temple pavilion called Honinbo from where he taught Go.